الفهرس 
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Abstract
Iron is the mast abundant element in the earth’s crust. Its
Hility, importance and essential ity in different aspects of lire are so great
hat it has been high-light,~ned in the Holy Quaran as ”We sent aforetime
our Messengers with clear signs and sent down with them The Book and
The Balance (of right and wrong) that men may stand forth in justice and
we sent down IRON in which is great might as well as many benefits for
mankind (Holy QuorLIn, Sorat (57), verse (25).
Iron deficiency anemia is the most common form of anemia
world wide. Helicobacter pylori is one of the most common human
bacterial infection in the world as it infects about one half of the world’s
population. H. pylori infection is common in Egypt and acquisition of
infection occurs early in life at a very young age. It is linked with
adverse spectrum of gastrointestinal clinical disorders as pep!ic ulcer and
cancer as the main reservoir is the human stomach. Many reports sho\\
also that this organism causes a variety of extraintestinal manifestations
in children including unexplained iron deficiency anemia in absence of
gastro intesti na I bleeding.
The present study wa, carried out in Banha University
Hospital _ Pediatric Department and Clinical Pathology Department to
study the prevalence of H. pylori IgG in iron defrciency cases. For this
purpose 79 children with mean age 45.3 ± 23.8 months, diagnosed as
having iron deliciency anemia, were enrolled in this study t<;Jgemer with
20 healthy children, matched for age and sex, as control group. Our 79
cases (group I) were subdivided into group 11, anemic H. pylori -ve,
and group III, anemic H. pylori +ve, while the control group was IV.
It is clear from this study that all the different anemic
groups showed sig.lli Iicantly lower Hb level than their controls. In
anemic H. pylori +ve, Hb level was significantly lower than that 111
anemic H. pylori -\ e cases. All the studied groups showed statistically
signiticant lower serum iron levels than health v controls. But both H. ~ .
pylori +n: and H. p> lori -ve patients did not show statistically signiticant
difference in serum iron levels. Serum ferritin level was statistically
signiticantly hig.her in healthy controls than serum ferritin of the other
three groups. Serum levels in H. pylori +ve patients were significantly
lower compared to H. pylori -ve cases. Total iron binding capacity was
signiticantly lower in control group than the other three studied groups.
It does not shov, an> signilicant difference between H. pylori -t-ve and H.
pylori -\C cases. H. pylori serum IGg was signiticantly higher in patients
compared to health) control g.roup. Anemic H. pylori +ve showed
statistically significant difference than anemic H. pylori -ve cases. No
significant difference between conllo!s and anemic H. pylori -ve cases.
The IgG positive cases represent 54.43% of the whole anemic patients
and only 10’% or the controls. ’The IgG % cases were highly statistically
significant than in control group.
So, in conclusion and for recommendation, patients with iron
deficiency anemia who are not responding to iron therapy and without
any apparent cause for their iron deficiency anemia should be
investigated for the presence of H. pylori. Cases who are proved to be
anagement.