الفهرس | Only 14 pages are availabe for public view |
Abstract - 71 - Summary, conclusion and recommendation SUMMARY, CONCLUSION AND RECOMMENDATION The adverse effects caused by high levels of dietary iron on copper metabolism come mostly from animal models. In humans, who frequently use supplements of vitamins and iron, this interaction has not been sufficiently studied, particularly in children. Controversial results in the literature encouraged us to carry-out a study aiming at verifying whether oral iron therapy would interfere with the nutritional copper status of a group of 29 anemic children where iron deficiency anemia was prevalent. fi..JJX ~ The study design included evaluation of body indicators of copper and iron before and after oral iron therapy. Significant changes of body indicators of iron ( hemoglobin level, serum iron, transferrin saturation %, serum transferrin and total iron binding capacity) after oral iron therapy denote correction of the state of anemia. Serum copper and serum ceruloplasmin were found to be significantly decreased after oral iron therapy indicating that oral iron used in treatment of iron deficiency anemia may carry the hazard of inducing copper deficiency. So, we recommend that all possible efforts and funds should be paid to prevent iron deficiency anemia and if it happens, copper supplementation should go hand in hand with iron therapy for these children. |