الفهرس | Only 14 pages are availabe for public view |
Abstract SUMMARY The present work was designed to study the correlation between methanol level and osmolal gap; and the utility of the later as an early detection procedure for methyl alcohol toxicity. This study was conducted as following, 30 patients of acutely methyl alcohol intoxication are chosen from the Emergency Room of Poison Control Center of Ain Shams University Hospital with another 10 normal persons as a control group. The following parameters were done on both groups: Measured osmolality, Blood urea nitrogen(BUN), Serum glucose and serum sodium for Calculated osmolality. So, osmolal J:!!J!c.an be obtained from the difference between measured and calculated osmolality. Also we measured Anion t:!Y!J.pH, Ethanol blood level and methanol blood level. We found that there is a highly significant correlation between methanol blood level and osmolal gap among all patients studied as r = 0.59605. Also, a significant correlation between methanol blood level and calculated osmolality among all patients studied as r = 0.47191. A highly significant correlation between methanol and measured osmolality among all patients studied as r = 0.79479. A significant correlation between methanol and anion gap among all patients studied as r = 0.33834. A significant correlation between methanol and pH among all patients studied as r = -0.54672. On the other hand there is no correlation between all the parameters and ethanol blood level which means that the changes in these parameters were due to the increase of methanol blood level with comparison with control group. |