الفهرس | Only 14 pages are availabe for public view |
Abstract SUMMARY The arm of this work is to evaluate the culture method In diagnosis of helicobacler pylori in patients with dyspepsia In comparison to the histological method with modified giemsa staining. To fulfill this aim ~0 patients with dyspepsia were included. The patients were subjected to the following: • Full medical history taking, • Thorough clinical exanination. • Routine laboratory investigation. • Upper gastrointestinal endoscopy and two biopsies were taken for bacteriological and histological examination. Helicobacter pylcri was detected by modified giemsa stain in 30 patients out of 50 (60%) and could be isolated by culture in 18 patients (36%) all of them were positive RP. by modified giemsa. So when modified giemsa is considered as a reference test senstivity, specificity, positive predictive valle and negative predictive value of culture method respictevely were 53.3%, 90%, 88.9% and 56.3%. As regard age and sex the incidence ofH.P. had no statistically significant difference in different age groups and in both sexes H.P. could be de tected in 7 patients out of 8 with peptic ulcer (87.5%) and in 5 ou: of 6 with duodenal ulcer (83.3%) with a statistically significant difference between patients with peptic ulcer and those without. H.P. could be detected in 11 out of 12 patients of dyspepsia with endoscopic picture of gastritis (92%). H.P. could be detected in 13 out of24 dyspeptic patients with chronic liver disease (5l%) and in 17 out of 26 dyspeptic patients without chronic liver disease with no statistically significant difference. Endoscopic gastriis was found in 8 patients out of 35 dyspeptic patients with histologies I gastritis (22.8%) and in 3 patients out of 15 patients without hsitological gastritis (20%) with no statistically significicant correlation b etween endoscopic and histologic gastritis. |