الفهرس 
Lipoproteins metabolismOnly 14 pages are availabe for public view
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Abstract
________________ 0ummary.& Conclusion
SUMMARY AND CONCLUSION
The aim of this work is to detect the role of high density
lipoproteins HDL and Lipoprotein (a) in protection of patients with
liver cirrhosis to develop coronary heart disease.
The study were included fifty two patients with chronic liver
disease with an age ranged from 25 to 65 years and were classified into
three classes according to Child classification [class A (mild), class B
(moderate) and class C. (severe). Also the study included fifteen
patients with coronary heart disease with an age ranged from 35 to 55
years. fifteen matched persons as control group.
Both patients and control were subjected to full history and
thorough clinical examination and then were investigated for:
1- Liver function tests (total protein, serum albumin, total bilirubin,
SGOT, SGPT, and alkaline phosphatase).
2- Electrocardiography.
3- Ultrasonography.
4- Total cholesterol.
5- Serum lipoprotein (a).
6- High density lipoprotein.
The results obtained were statistically analysed and revealed that
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_________________ CSummary &) Conclusion
’” There was highly significant decrease in Lp(a) in cirrhotics compared
with controls.
’” There was highly significant decrease Lp(a) in cirrhotics compared
with IHD patients.
’” With increasing the severity of hepatic cirrhosis, Lp(a) decreased
significantly from one class to other.
’” There was no statistical difference in HOLc between cirrhotics and
controls but there was significant decrease in HOLc between
IHD patients and cirrhotics.
’” The mean HOLc for cirrhotics (59.57 mg/dl) was above the risk
value for IHD. (30 mg/dl).
* There was significant decrease in total cholesterol between cirrhotics
and control
We can conclude that low concentration of lipoprotein (a) in
liver cirrhosis may play a role in protection of cirrhotic patients from
coronary heart disease and Lp(a) is a strong risk factor for the
development of premature coronary heart disease independent of total
cholesterol.