الفهرس 
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Abstract
SUMMARY& CONCLUSION ---------4(115)
Summary and Conclusion
For many decades, the importance of subclinical hepatic
encephalopathy has been a source of controversy within the
hepatologic -community. This syndrome was defined as a
condition in which patients with cirrhosis, regardless of the
etiology, demonstrate a number of quantifiable neurophsychatric
defects, yet have a normal mental and neurological status to
global clinical examination (Gitlin, 1988).
There is no data concerning the extent of this problem In
Egypt.
The neuropsychologi cal defects In subclinical hepatic
encephalopathy may have a negative effect on patients daily life
especially fitness to drive a car.
Early diagnosis of subclinical hepatic encephalopathy is
recommended as this syndrome may be fully reversible with
successful treatment.
So the aim of this work is to study the prevalence of
neurophysiological and neuropsychological defect in chronic
Liver diseases.
This study comprised 30 patients with cirrhosis due to viral
hepatitis C (17 compensated and 13 decompensated), 30 patients
with fibrosis due to hepatosplenic schistosomiasis (22
compensated and 8 decompensated), and 20 healthy volunteers
as control.
All Jlllticnts will he slIlJl1liftel1Hi thl’ following:
(1)-. l l istorv laking with sp,~ciol slrcss 0/1 .
,~Age,
”’Ilistory of hilhm7,ial infe: tation,
”History of operation, hlond Irnnsfusion or cont:lcl tojaumliccd
palients and
*1iistmy of enccph:llop:llhy (Ihose with history of evident
enceplmlop:lthy were eXc!lllkd),
Cll::C:.Jinica! eXOl/lill(lt ion,
*Manifestations of chronic liver disease
*Manifcsta!ion of orgal’ic neurologic:11 disease ( those with
mgauic neurological diselse were excluded)
(3Hmaging.
,,(4)~RoufiIlC laboratoty ilVCsfigl1tiolls
(5J~,Signl0idscoJ}Y’
(6)~lVr?-uropsychologic;al tests.
’fNUlllher cnl1l1eetion test (NCT)
*Symhnl digi1 Icsl (SilT)
(7)- Electrocnccpl/(/{ogi’l1111 (l’;EC,’).
1\ prcvnknce,l!’ sui’ c1inienl hep:llic elH’eph:dnpnthy in the
[orm orahnorlllal nUlllhc~r conneetioll lest ,’,core W:IS ’i~.\’/\,in nll
studied pnticnts was !lllnd being 70’j\, in cirrhosis due to viral
.
SUMjlf/tJll’&JcQl’lf”J-JJJlQI’l ...
hepatitis (. and 46./’1.. III patients with hcpntosplcnic
schistosomiasis and non n control,
The prevalence 01’ SI IE according to Ihe number connection
tcst score was higher in viral hepalilis ( ’ and illClcasing rh1l11
12..10% 10 75.00’% in Child-I’llI’’’ I~rade A and II’Tslwdively.
A!so illCreasing Iio III II’; .\0% and )5.00”,;, in (’hildP””Jt p.rnde.
;\ and n .respectively ill licpatospcnic schislo.’;()miasis .
While EEG showed; lower percentage in each gronp heing
abnormal I R nut of 10 111 cirrhosis d”e fo viral hep,tfifis (’
(60%), and f 5 out of’ 10 pafienf (’iO’Y;,) wilh hcp;llosplcnic
schistosomiasis. Also lhe percenlage or palicnl.~ vvilh positive
FEU findings ilicreasingiom ri7.0S% 10 Hl(J)’j;, ill (’hild-Pugh
grndc A and n respectively in hepafilis (’ 1.’rouP.
Also increasing Irom i0. i5% (0 71.00 % 111 (’hi!d-Pllgh
grncie ;\ allll II le.sped’veiy ill schis(osol”iasis group. and
This study silmved <1130 the p~;y(’homcfric fesl.s were
extremely signilic:mi iliH ;;’.I~;1live coru-lntion ill hCp;llilis (’
groups and extremely Sipiir:’iml witl: po.silive eorrc!<Jiiol1 iI1 ’;
sei;isfli.soll1iasi.s grnllp.
Regnrding cOll1paris(:1 ”,” ween C:l~W and contro!s, there
number 1’()11I1Cclion Ie:;: ,md
symhol digil lesi n( r:ii levels