الفهرس 
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Abstract
Conclusion
o’J lit-(.-
CONCLT)STO’JV
Nasal polyp has multifactor etiology, allergic cause play important
role and the inflammatory cause has a respected role also, so we must
design a regimen of management for each group and the aim of each
regimen to decrease the recurrence of the nasul polyp. In allcrgic group
premedication with corticosteroid is essential for prevention of the
recurrence. In inflammatory group of patients premedication with good
antibiotic is important. In aspirin sensitive allergic patients we must
desensitize those patients by local irrigation to the nose with lysine
acetylsalicylate to prevent recurrence.
Eosinophil play major role in nasal polyp formation, JL-5 playa
pivotal role in recruitment of the eosinophil to the nasal polyp so in
another hand Antileukotriens was used strongly in treatment of the nasal
polyp and its prevention. ”1
RANTeS (regulated on activation, Normal T cell Expressed and
secreted) is a potent mediator of eosinophill chemo taxis in vitro and of
leukocyte recruitment, studies have rcgularly detected Ri\NTES within
polyp stroma so this finding direct our attcuion to the management of
nasal polyp based on this fact.
Myofibroblast playa significant role on the growth of nasal polyp.
The number of myofibroblasts was increased in the pedicle of nasal
polyp which make constriction and so impair drainage which lead to
edema of the t issue and so enlargement of the polyp.
Role of noxious environmental pollutants as a possible trigger in the
inflammatory reaction w¥ discussed in many studies, which display the
_ro_le of,environmen~tal.~_~l_luta.~n.t ._in~t~he~e~·tio;~p!a-~tLhogenesis of the nas_al
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