الفهرس 
Material and methodsOnly 14 pages are availabe for public view
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Abstract
Summary & Conclus m
SUMMARY &. CONCLUSION
Obesity is associated with higher incidence of cardiovas ular
diseases. It is well known that long-standing obesity is assoc ited
with preclinical and clinical left ventricular dilatation, with. eart
failure frequently being the ultimate cause of death in morl idly
obese persons.
Little information on the possible influence of obesitj on
diastolic function is available. Thus we studied 46 asymptor atic
obese subjects aged 34.5±8.1 years, ranging 19-49 years with ody
mass index more than 27 kg/m2. The obese subjects were mal bed
with the control subjects for mean age, and mean sex.
The following results were obtained:
Right ventricular dimension was greater in the obese ~ cup
than the control group but the: difference was non significant (: 03+
0.7 versus 1.9+0.5, p >0.05).
The mean. Peak early filling velocity of tricuspid , Live
(Tricuspid E) was lower in the obese group than in the C( itrol
group and the difference was. highly significant (52.01 +11.9 v rsus
65.5±7.6 em/sec, p <0.01).
The mean Peak early filling velocity of mitral valve (mit] II E)
was lower in the obese group than in the control group an Ithe
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The mean peak atrial filling velo ity of tricuspid , ilve
(Tricuspid A) was higher in the obese gr up than the contr 1and
the difference was highly significant (57 2±11.7 versus 37. :+5.5
em/sec, p <0.01) ..
Summary & Conch iion
difference was highly significant (68.72+ 4.41 versus 78.6 :11.1
em/sec, p <0.01).
The mean Peak atrial filling velocity 0 mitral valve (mil al A)
was higher in the obese group than the c ntrol and the diffi renee
was highly significant (66.19+13.29 vers s 49.27+8.52 em .ec.p
<0.01).
The mean tricuspid E/A ratio was 1 wer in the obese ~roup
than the control group and the difference w s highly significa t (0.9
±0.3 versus 1.8±0.3, p <0.01).
The mean mitral E/A ratio was lowe in the obese grot: ) than
the control group and the difference was ighly significant 1.09±
0.33 versus 1.62±0.47, p <001).
Among the studied obese subjects the e were 31 obese Sl bjects
(67.4%) having abnormal tricuspid E/ ratio (sl ), 24 ibese
subjects (52.2%) having abnormal mitra E/A ratio and 21 obese
subjects (45.7%) having abnormal both itral and tricusp d E/A
ratio compared to the control subjects in hom none had ab ormal
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Summary & Conclu [lI1n -
EfA ratio and the difference was statistically highly signif cant
(p<O.Ol).
The degree of obesity showed a positive correlation vith
abnormal EfA ratio (p<0.05).
Tricuspid first half filling fraction was lower in obese su jects
than in. the control subjects and the difference was h ghly
significant (47.2+8.4) versus (60.9+5.0) (p<O.Ol), where non fthe
control subjects have first half filling fraction less than 0.55 .here
were 40 subjects of the obese have one half filling fraction les than
0.55.
Among the studied obese subjects there were 30 sulects
(65.2%) with combined abnormal both tricupid FHFF and tric ispid
EfA ratio. So the study came to the following conclusion:
_ Right and left diastolic dysfunction are common in obese su Ijects
and the right being more common.
_ Abnormal first half filling fraction as a parameter of di: stolic
dysfunction is more prevalent among obeses than abn rmal
tricuspid EfA ratio.
_ Diastolic filling abnormalities were more prevalent in rna [crate
and severe degree of obesity & the degree of obsity s’ owed
apositive correlation with abnormal tricuspid EfA ratii and
abnormal first half filling fraction.
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