الفهرس 
Myocardial ischemiaOnly 14 pages are availabe for public view
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Abstract
ith the wide spread prevalence of coronary artery disease, many
non-invasive tests have been evaluated for their ability to detect
myocardial ischemia.
One of these non-invasive tests is echocardiography, which is
widely used for detection of ischemia and evaluation of left ventricular
function because of its ability to detect myocardial thickness and wall
motion in real time. Yet, conventional 2D echocardiography suffers from
the disadvantages of a qualitative method and it is subjective and
experience dependent.
DTI is a new ultrasound technique that is based on colour imaging
principles and allows quantification of intramural myocardial velocities
by detection of consecutive phase shifts of the ultrasound signals
reflected from the contracting myocardium.
The endocardium moves faster than the epicardium during
myocardial contraction, reflecting the rate of increase in wall thickness.
Therefore, the velocity gradient between the endocardium and epicardium
in systole is an indicator of regional myocardial contraction.
MVG is defined as the difference in myocardial velocity between
the endocardium and epicardium divided by the myocardial wall
thickness if the transmural velocity profile is approximated as linear.
The current study included 35 patients with CAD as documented
by history, clinical examination, resting ECG and coronary angiography
and divided into 2 groups:
Summary
120
1. Group (I): included 20 patients with coronary anatomy
suitable for PTCA. They were subdivided into 3 subgroups
according to target vessel:
- Subgroup (IA) had done PTCA for single LAD lesion and
included 7 patients .
- Subgroup (IB) had done PTCA for single CX lesion and
included 7 patients.
- Subgroup (1C) had done PTCA for single LAD and CX
lesion and included 6 patients.
2. Group (2): Included 15 patients who were candidate for
coronary artery bypass graft.
We had measured MVG before myocardial revascularization in 16
segments of LV in the long parasternal view, apical 4 chamber view and
apical 2 chamber view by the pulsed wave method. Then, MVG was
reassessed before discharge by the same parameters.
We found that MVG is reduced in ischemia and is increased after
myocardial revascularization by PTCA and CABG in most of the 16
segments of LV with significant values.