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Abstract The material of the present study comprised one hundred subjects [ Twenty with isolated rheumatic polyarthritis (group I), twenty with rheumatic MS (group IT), twenty with rheumatic MR (group Ill), twenety with rheumatic double mitral lesion (group IV) and twenty as normal healthy control subjects ] to evaluate the coexistance of MVP and rheumatic fever. All groups were studied by echo. Doppler and the following results were obtained:- * Significantly higher prevalence of unequivocal MVP in rheumatic heart disease as a whole versus controls (P<O.05). * Significantly higher prevalence of unequivocal MVP in isolated rheumatic MR versus control (P<O.05).. * Insignificant prevalence of unequivocal MVP in isolated rheumatic MS, double mitral lesion as well as isolated rheumatic polyarthritis (P>O.05). * A positive correlation was found between MVP and the following parameters: 1- Age (adult). 2- Female sex. 3- Systolic click. 4- Third heart sound. 5-MR. 6- End diastolic diameter. The results were tabulated and statistically analysed. PageNo. 92 * Rheumatic heart disease as a whole had a significantly higher prevalence ofMVP than healthy controls. * Patients with pure MR had the highest prevalence and those with pure MS had the lowest prevalence, and this is well appreciated by the underlying pathophysiology of valvular lesion. * Patients with isolated rheumatic polyarthritis showed insignificant increase ofMVP prevalence than control subjects. * A postinflamatory MVP may be the underlying etiology of pure MR. UMlTATION * Small number of patients. * Microscopic examination of spicemen from leaflets to define pathology was not done as the study is a clinical one. PtlpNo. 9J |