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Abstract The aim of the diagnostic value of versus surgical open head and neck masses.present work is to compare the fine needle aspiration cytologybiopsy as a diagnostic tool toThe material of this work included sixty nine patients with different head and neck lumps, 32 males and 37 females with an age ranging between one and seventy years. The cases were classified according to the anatomical sites into 5 groups: lymph nodes masses, thyroid gland masses, salivary gland masses, nose and paranasal sinuses masses and finally the miscellaneous masses group. Lymph node masses group: Out of 7 cases diagnosed cytologically as benign lymph node lesions, one case was proved histopathologically to be malignant, giving an accuracy of 85.7%. Out of 13 cases diagnosed cytologically as malignant lesions, 2 cases were proved histopathologically to be benign, giving an accuracy of Thyroid gland masses group: There were 14 cases which were proved both cytologically and histopathologically to be benign.Also There were 5 cases which were proved both cytologically and histopathologically to be malignant, the accuracy in this group was Salivary gland masses group: Out of cases diagnosed cytologically as benign salivary gland lesions,one case was proved to be malignant by histopathology giving an accuracy rate of 87.15%. While there were 2 cases which were proved both cytologically and histopathologically to be malignant giving an accuracy of Nose and paranasal sinuses group: There were 7 cases which were proved both cytologically and histopathologically to be benign. Also There were 2 cases which were proved both cytologically and histopathologically to be malignant. The accuracy in this group . Miscellaneous group: Out of 7 cases diagnosed cytologically as benign,one case was proved to be malignant by histopathology giving an accuracy of 85.7%.There were 4 cases which were proved both cytologically and hisopathologically to be malignant giving an accuracy |