الفهرس 
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Abstract
The aim of this is to assess different modal iti es
(biochemical, radiological, biological and morphological) for diagnosis
of renal transplant rejection. This study comprised 30 patients, 5
of them had no rejection, while the rest had 37 rejection episodes.
It could be observed that with blocnemt cal and morphological
parameters, biphasic changes are noted during the course of a rejection
episode. On the other hand, with biological parameters this
changes are at random and were even observed in cases that did not
suffer from single rejection episode. Fine needle aspiration cytology
provided the highest sensitivity and the best specificity followed by
serum c reati ni ne esti mati on.
On the basi s of our own observati ons , frequent estimati on of
serum creatinine constitutes the central mean of survaying the
allograft function. When an elevation in its value is noted the
second logic step in our view is to carry out ultrasonographic examination
of the graft. This is non-invasive, painless and bedside procedure
which l’«Juld readily eleminate such causes as urinary tract
Obstructions, leaks and peri-renal collections. With a negative ultrasound
examination, an aspiration cytology is indicated since it is a
sensitive, reproducible and provides a morphological basis for the
diagnosis of acute rejection. It is harmless and could be repeated.
Tru-cut biposy should only be used in difficult cases with unsettled
diagnosis. Radionuclide imaging should be only carried out when the
renal vascular integrity is suspected as a cause of deterioration of
the graft functi on.