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Abstract OUT study was carried out on 29 patients suffering from rheumatoid arthritis diagnosed according to the American collage of rheumatology revised criteria for rheumatoid arthritis (Arnett et at; 1988). These patients were divided into 4 groups according to the disease activity using Mlu{ya and Mace Score (1981). All patients were subjected to the foUowi]]g~ .:. Full history taking and complete clinical examination, .:. Locomotor system examination with stress on the parameters ofdisease activity ofAA . •:_ Laboratory investigations analysts includiog the following: _ El)throcytl;; sedimentaLion rate, _ Haemoglobin percent. _ Latex fixation test for rheumatoid factor, _ Measurement of serum cortisol level at 8 a.m., p.m, using radioimmunoassay (RIA) Kit in both patients and control group which included 10 healthy individuals, |