الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
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Abstract
Hepatitis C virus infection is a major public health problem ifldwide, the disease prevalence In Egypt is considered the highest obally, and being accused to be the main cause of chronic liver illness. The relation between HCV and other diseases that affect a large sector of !th3eEgyptian population, is an important issue to address. Schistosomiasis, although being a subject of much debate IDceming its association with HCV, yet it is believed to be both related, d both affecting a large sector of the rural Egyptian population. HCV is also a matter of controversy, when discussing its role as a ’,k factor of developing diabetes mellitus (DM), the disease known to be ’thmultiple etiologic nature and a pandemic image. ’The present study was conducted in order to: ’.lnvestigate the possible association between hepatitis C virus infection and diabetes mellitus. I. Investigate the possible association between hepatitis C virus infection and schistosoma! hepatic fibrosis (SHF) with or without super added diabetes mellitus. .Detect other possible risk factors that might affect such association. Three hundred individuals were studied, and divided into six different ’Oups including fifty individual each, and marked: ;Patients with Type 1 DM Patients with Type 2 DM [.Patients with SHF i.Patients with Type 1 DM and SHF .Patients with Type 2 DM and SHF Control group matched with other groups as regards age, sex, socioeconomic standard. AlI study subjects were submitted to the following: I. Filling a predesigned questionnaire sheet including personal, habitual, demographic data and medical history about (possible risk factors, schistosomiasis and diabetes mellitus). o2.Full clinical examination (general and systemic) with calculation of the body mass index (BM!). J.Laboratory investigations using urine, stool, and blood samples. The blood was recruited to perform: a-Estimation of Liver enzymes (ALT & AST) b- 2 hours post prandial glucose for diabetic cases c- Oral glucose tolerance test for all non diabetic cases (fasting and 2 hours post glucose load samples) d- Estimation of glycosylated haemoglobin level (HbAle) for the diabetic cases e- Detection of anti-HCV immunoglobulins using 3rd generation EIA (ELISA) ~.Data collected were coded, tabulated and analyzed using SPSS and EPI Info software packages. . tical analysis of the data revealed the following results: les accounted for (53.3) of the sample cases, while females represented (46.7).