الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
 |  | from | 194 |  |  |
| | | from | 194 | | |
Abstract
Toxoplasmosis is one of the most important diseases not only in Egypt but also all over the world. It is ca use d by Toxoplasma gondii protozoa, which can be tran smitted to humans either congenitally or after birth. Congeni tal toxoplasmosis is no doubt, the most serious form of the infection. It was assumed that congenital infection could happe_n only in active infection, but it now appears that parasitaemia can result from chronic infected mother. Most often, when a mother is infected during pregnancy, the outcome is a normal uninfected infant, but spontaneous abortion, stillbirth or deliwvery of a premature or full-term infected infant may result. In infants born to mothers infected during the first trimester, congeni tal infection is least common, but disease is most severe in infants born to mothers infected during the the third trimester. The foetus is at risk whether or not the mother, because the becomes localised in the central nervous infection is symptomatic in parasited usually system. As mental retardation is one of the most important lanifesta t ions of Toxoplasma infection, the aim of this york was to study the percentage of infection of toxo- p1asmosis among the mentally retarded children in Alexandria and to study the possible relation between toxoplasmosis and mental retardation. A random sample of 208 children were chosen from the three mental health rehabilitation schools in Alexan They were subjected to the following: 1- A questionnaire sheet was filled to study certain factors and relation of some clinical manifestations among the childrens and their mothers, sisters and brother s . 2- Collec tion of finger-prick blood DROPs on filter p&per was done for serological diagnosis by IFAT and IHA’!’. The data was subjected to statistical analysis. Inter pretation of the results was based on the criterion that the specimen was considered positive for Toxoplasma anti bodies when positive reaction was achieved in one or both serological tests. So the results obtained in this study could be summarized as follows: 1- The percentage of Toxoplasma infection was 27.4among the examined children. 1- There statistically was no age and rank of the examined 3- The of infection per-cen tage between relationship economic level of the children highest children from among and lowest (16.7) among 4- It found that the was significantly higher among than 50 (37.1) while it with LQ. more than 50. 5- As regards the clinical higher percentage those percentage the was sex, and the infection. children was affected the aocio by where the was rate the middle class (33.0) from the high class. ~ of infection was children with I.Q. less only 23.3among those a significantly of children manifestations from macrocephaly followed by retardation examined children had 6- Th e of mental history the brothers & sisters a significant relationship 7- The percentage distribution significantly higher among erienced abortion, stillbirth G from the above results, Toxoplasma infection could be of mental retardation and has other and neurological ocular respo”sible for a certain epilepsy. .of the were complaining with of children it and epilepsy among the infection. Toxoplasma infection was whose mothera exp or premature labour. can be that concluded responsible for the aetiology a role the aetiology of in disorders. It also can be of the abortiol1s, stillbirth premature labours.