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Abstract Ozone is triatomic oxygen (O3). It is an extremely potent oxidant. It is created by solar radiation, lightening, and reaction of hydrocarbons and nitrous oxides in the presence of sunlight. CFCs damage the protective ozone layer. Ozone depletion will increase the amount of UVB, which will increase the risk of health effects. Chronic contact with O3 can be deleterious for the skin. Progressive depletion of antioxidant content in the stratum corneum occurring as a result of O3 exposure can lead to a cascade of effects resulting in an active cellular response in the deeper layers of the skin leading to inflammation and affecting skin biology. On the other hand basic and clinical work has shown that transient treatment and small O3 doses can reactivate useful body functions and might display therapeutic activity. |