الفهرس يوجد فقط 14 صفحة متاحة للعرض العام
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المستخلص
The study involves prospective and retrospective GERD of 40
patients with symptomatic GERD grades (II, III , IV) who will be
allocated to one of two groups:
Group A: 20 patients undergoing medical treatment
Group B: 20 patients undergoing laparoscopic treatment of their
acid reflux
Pre-study will be compared with post-study with a 9
Month follow up, depending on:
• Symptomatic relief
• Healing of oesophagitis
• Recurrence (judged by endoscopy)
• Occurrence of complications
• Tolerance to medical treatment
Comparison between groups would be carried using chi-squared
analysis for non numerical data.
In this study, there’s obvious significant improvement in the
lower esophageal sphincter (LES) length and LES pressure in the
surgical group, with a concomitant improvement in healing of
esophagitis and symptomatic relief.
Concerning the LES length and LES pressure a significant
increase in both length and pressure where noted in the post
surgical group.
Concerning the healing of esophagitis, surgery proved to be superior
to medical treatment in healing of esophagitis, while surgery succeeded
in stepping down the stage of esphagitis to 80% having no
esophagitis at all & 10% in stage I & another 10% in stage II,
medication left 70% in stage II & 20% is stage III.
Concerning symptomatic relief, surgery also proved to be
superior to medical therapy in relieving symptoms of GERD,
especially regurgitation, with a success of 100% in the surgery
group, while medication failed to relief regurgitation in any patient
who suffered this symptom. i.e.(0% success).
Surgery was found to be slightly superior to medication in
relieving heart burn with a success percentage of 80% compared to
60% in the medical group, and a lesser significance in reliving
dysphagia in which success percentage was 80% in the surgical
group compared to 66.6% in the medical group.
Key words:
GERD (gastroesophageal reflux Disease), B.E (Barrett’s
esophagus), H.H (Hiatus Hernia), PPI (proton Pump
Inhibitor), LES (Lower esophageal sphincter), SCJ
(Squamocolumar junction), TLESR (Transient lower
esophageal sphincter relaxation).