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العنوان
A retrospective comparative study evaluating .
the incidence and severity of chronic graft-versus-host disease
in myeloablative and nonmyeloablative allogeneic hematopoietic stem cell transplantatiO
المزمن فى كل من زراعة النخاع العظمى الكلى
وزراعة النخاع العظمى منخفض الكثافة
الناشر
CAIRO.medicine.Internal medicine,
المؤلف
SAMY, MARWA MOHAMED NABIL.
تاريخ النشر
2004 .
عدد الصفحات
215ص.
الفهرس
يوجد فقط 14 صفحة متاحة للعرض العام

from 226

from 226

المستخلص

Results of our study showed no significant difference either in incidence or severity of cGvHD between both groups. These results were consistent with a study done by Mielcarek et al, on 44 patients who underwent nonmyeloablative HSCT compared to 52 underwent myeloablative HSCT (median ages, 56 and 54 years, respectively). The nonmyeloablative transplantation regimen consisted of low-dose TBI, proceeded in some patients by fludarabine administration and followed in all patients by immunosuppression with MMF and CSP. Those who underwent myeloablative HSCT were conditioned with different TBI- and non-TBI–containing regimens and received CSP plus methotrexate or MMF for GvHD prophylaxis. There were also no significant difference in the cumulative incidence of cGvHD requiring treatment (73% vs. 71%; p = 0.96).


Key Words :


Avascular Necrosis – Busulphan –Dendritic Cells.