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Abstract
Dyslipidemia is one of the major risk factors for coronary artery diseases in which circulating levels of lipids or lipoproteins fractions are abnormal because of genetic and/or environmental conditions that alter the production, catabolism, or clearance of plasma lipoproteins from the circulation.
Hypercholesterolemia or hypercholesterolemic serum lipoproteins promote monocyte adhesion to endothelium and expression of several adhesion molecules.
Adhesion molecules include selectins, immunoglobulin superfamily, and integrins. L-selecting is cell membrane surface receptors on neutrophils, monocytes, and lymphocytes, and is responsible for attachment of leukocytes to inflamed endothelium.
The aim of this work was to study the relationship between dyslipidemia and expression of L-selecting on leukocytes.