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Abstract
The autoimmune disorder,rheumatioid arthritis, (RA) occurs is about1%-2% of the human population. The disease is more prevalent in women than in men, but in the reproductive years the ratio may be high . Antiheumatic drugs (non-steroidal anti-inflammatory drugs (NSAIDs) and disease-modifying antirheumatic dragus(DMARDs) are basic therapy for patients with rheumatoid arthritis because of their analgesic and anti-inflammatory properties.