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Abstract
Nasopharyngeal carcinoma (NPC) is an epithelial malignancy occurring worldwide. It is aggressive, with a high incidence of loco regional lymph node spread as well as distant metastasis at presentation .The 1-year mortality for NPC patients may be up to 90% when distant metastasis is found before treatment. Therefore, the presence of distant metastatic lesions greatly influences prognosis and treatment strategy.
Positron emission tomography (PET) using 2-(18)F-fluoro-2-deoxy-D-glucose (FDG), a radioactive derivative of glucose, is an advanced imaging tool, based on the increased glucose consumption of cancer cells , it has made a major impact on the detection of distant metastases in NPC patients with primary lesions and stage M0 disease.