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Abstract
Colorectal cancer is the second leading cause of cancer-related deaths in western world.
The prognosis of colorectal cancer closely related to disease Stage at initial diagnosis & ability to achieve surgical clearance. Thus, accurate preoperative staging is of at most importance for optimal therapeutic planning.
Although conventional preoperative staging & evaluation of colorectal cancer has been performed by computed tomography (CT), ultrasound (US), magnetic resonance (MR) & positron emission tomography (PET), there is no ideal imaging modality in terms of diagnostic accuracy& staging due to potential limitations of these imaging modalities.
Several studies have investigated the potential role of CT in the diagnosis and staging of colorectal cancer, with the accuracy rate ranging between 64% and 81%.
Although CT has limitations in terms of detecting lymph nodes that contain tumor, preoperative CT is useful for planning surgery.
PET/CT is superior to CT alone because its PET component depends on the physiologically mediated distribution of glucose uptake, rather than on the anatomic and structural characteristics of tissue.