الفهرس 
introduction
photochemotherpy (puva)Only 14 pages are availabe for public view
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Abstract
This study was carried on 40 psoriatic patients and 10 healthy controls in our Department of Dermatology Venereology and Andrology, Assiut University Hospital. All the patients were subjected to the following:
a) Clinical assessment of psoriasis vulgaris was done through history and psoriasis area severity index (PASI).
b) ELISA technique was used to study the serum levels of (sIL-2R) and (sICAM-1) in all psoriatic patients (before and after treatment) and controls.
The patients who continued treatment (n=30) were divided into 2 groups:
Group I: (n=15) exposed to PUVA alone for 4 weeks.
Group II: (n=15) exposed to PUVA with topical steroid (Betamethazon) for 4 weeks.
Our psoriatic patients have significantly higher serum sIL-2R and sICAM-1 than controls. Treatment of psoriasis with PUVA alone and PUVA with topical steroid for four weeks resulted in significant lowering of PASI and serum levels of sIL-2R and sICAM-1.
Comparing the two lines of treatment, PUVA and topical steroid was found to be more effective treatment than PUVA alone both clinically and serologically. This was clarified by the more marked decrease in the levels of PASI and serum sIL-2R.