الفهرس 
INHALATIONAL ANESTHETICSOnly 14 pages are availabe for public view
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Abstract
Organ toxicity is rare in patient exposed to inhaled anesthetics, but it may result in severe, potentially life threatening multiple organ damage and so the means by which inhaled anesthetics causes organ toxicity in experimental animals and man have been investigated intensively.
Sevoflurane, a new inhaled anesthetic, is characterized by pleasant non-irritant odor allow inhalational induction of anesthesia, cardiovascular stability, safety in ischemic heart disease, minimal respiratory depression does not affect hepatic perfusion, oxygenation or metabolic function and not potentially hepatotoxic as halothane minimal effect on cerebral blood flow and it has relaxant effect and augments the action ofneuromuscular blocking agents.
There is controversy about the effect of sevoflurane on the kidney as its metabolism liberate inorganic fluoride which may reach the proposed toxic threshold of 50 umol/L in some cases but there is no reports of renal troubles caused by fluoride produced by its metabolism and also there is controversy about safety of sevoflurane use in low flow, Organ toxicity is rare in patient exposed to inhaled anesthetics, but it may result in severe, potentially life threatening multiple organ damage and so the means by which inhaled anesthetics causes organ toxicity in experimental animals and man have been investigated intensively.
Sevoflurane, a new inhaled anesthetic, is characterized by pleasant non-irritant odor allow inhalational induction of anesthesia, cardiovascular stability, safety in ischemic heart disease, minimal respiratory depression does not affect hepatic perfusion, oxygenation or metabolic function and not potentially hepatotoxic as halothane minimal effect on cerebral blood flow and it has relaxant effect and augments the action ofneuromuscular blocking agents.
There is controversy about the effect of sevoflurane on the kidney as its metabolism liberate inorganic fluoride which may reach the proposed toxic threshold of 50 umol/L in some cases but there is no reports of renal troubles caused by fluoride produced by its metabolism and also there is controversy about safety of sevoflurane use in low flow