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العنوان
Studies on the relation between cholinesterase enzyme activity and carbohydrate metabolism \
المؤلف
Hassan, Mohamed Hanafy Ahmed.
هيئة الاعداد
باحث / محمد حنفي احمد حسن
مشرف / عمر احمد زكي
مشرف / محمود هاني ايوب
مشرف / محمود هاني ايوب
الموضوع
Cholinesterase genes.
عدد الصفحات
106 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
1/1/1979
مكان الإجازة
جامعة عين شمس - كلية الطب - الفسيولوجيا
الفهرس
Only 14 pages are availabe for public view

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from 125

Abstract

The relation between cholinesterase enzyme activity and carbohydrate metabolism was investigated in rats using the cholinesterase inhibitor prostigmin in a dose of 0.2 mg//Kg body weight.
Study of the effects of prostigmin administered for different periods on blood glucose and cholinesterase was carried out on fasting rats, A significant rise of blood glucose levels after 15 min, 30 min and 45 min. Changes of blood glucose level after 60 min of prostigrain were, however, insignificant. On the other ha.nd, insignificant changes In blood cholinesterase activity was observed at 15 min and 45 t«in; but 60 min after prostigmin the blood cholinesterase activity was significantly diminished, Effects of prostigmin were also studied on fasting fits loaded with glucose (2.5 g/Kg body weight). After min the blood glucose and the liver glycogen were sig- ttcantly higher than the control group but the changes in tele glycogen o • blood cholinesterase were insignificant.
lor atropinization prevented the significant results. The pets of prostigmin on blood glucose and liver glycogen ?peared, however, after 60 min but the muscle glycogen Bd a borderline significant increase above the control), This effect was also prevented by atropinization of Ls before prostigmin.