الفهرس 
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Abstract
Comparative effectiveness of patching and atropine as treatment for amblyopia was evaluated in 50 children younger than 8 years.
Substantial improvement in the visual acuity of the amblyopic eye occurred with both patching and atropine treatment regimens.
Improvement was more rapid in the patching group, but by 24 weeks, the difference in mean visual acuity between groups was small and clinically non significant.
The difference between the two groups in the percentage of patients meeting the criteria for successful treatment was also small (77% of patching group and 71% of atropine group).
Although no cases of persistent treatment-related decrease in the sound eye acuity occurred in either group, 2 patients (8%) in the atropine group compared with one patient (4%) in the patching group had a measured reduction of visual acuity in the sound eye by one line follow- up examinations, however, in alt cases with follow-up information, visual acuity in the sound eye returned to its pre study level.
One potential concern with atropine use would be the light exposure of the retina from the dilated pupil. Although, sun glasses were provided to our patients and hat wear was recommended out doors to m inimize the s un light exposure, it’s believed that a few months of atropine use doesn’t have a deleterious effect on the
retina. (The pediatric eye disease investigator group, 2002).
The burden to administer amblyopic treatment in children falls on the parent. One of the rationales for atropine use has been that t has higher degree of acceptability by patients and parents than patching.
Compliance to treatment in this study was excellent in (48%) Of children in patching group compared with( 77%) of children in atropine group which has a clinical significance improvement of visual acuity by 3 or more lines occurred by (80%) of children.