الفهرس 
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Abstract
Beside the established use of bone marrow trans¬plantation (BMT) as a successful therapy for a wide variety of hematologic and non-hemato logic diseases, it seems likely that in the near future BMT will be attempted as a therapy for any variety of malignant neoplasms that is sensitive to irradiation and/or chemotherapy.
The transplants are. In most instances, frcn a sibling donor who is genotypicaliy HLA identical with the patient and without a major ABO incompatibility.
The role of ABO blood group Incompatibility hae been analysed in several studies with the conclusion that it is not a major obstacle to successful transplantation,
however, major ABO incompatibility does present the threat of severe hemolytic reaction during marrow infusion, To circumvent hemolysls, other investigators have subjected recepients to extensive pre-transpiant plasmapheresis to reduce the i sohemagglu tinin titres. This procedure lias also been complete with either in vivo antibody absorption through the administration of incompatibile red cells or blood group substance, or in vItro antibody adsorption with immune-adsorbent columns