الفهرس | Only 14 pages are availabe for public view |
Abstract Non—ster-oidal antiinflarnmatory drugs (NSAIDs) are commonly prescribed in clinical practice. They are an integral part of therapy in rheumatic disorders. Numerous NSAIDs have been developed and a large number were under trials to give maximum antiinflammatory effects with low toxicity. Gastroduodenal mucosa carries the main brunt of NSAID—assocjated side effects. NSAIDs can induce various degrees of gastroduodenal lesions including inflammations. hemorrhages. erosions and ulcers. Some investigators reported an extremely poor correlation between the endoscopic gastroduodenal findings and the subjective symptomatology. Accordingly, the aim of the present study was to study the incidence of gastroduodenal lesions in asymptomatic persons on chronic NSAIDs. This study was carried out on fourt.y asymptomatic patients taking NSAIDs for 3 months or more, as well as twenty control subjects. |