الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
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Abstract
Along with the introduction of antibiotics, improvement have been made in diagnostic bone imaging techniques and in microbiologic techniques, including antibiotic sensitivity testing. Furthermore, a more aggressive approach based on early operation is common. All of these new developments in treatment would facilitate a changing pattern of bone and joint infections. In addition, changing in the properties of bacterial virulence may influence the pattern of infection. So this work aimed to the study of the infrequent causative agents of bone & joint infections with special reference to coagulase negative staphylococci and ~.albicans. -The present work included lD6 patients suffering from bone and joint infections attended the Sunday and Tuesday outpatient clinic of Al-Hadra Orthopaedic and Traumatology University Hospital of Alexandria in addition to patients notified by the causality department and those notified by the orthopaedic wards, from September 1991 to August 1992. Detailed history, including personal, socioeconomic level, associated bone diseases, bone infection, interference, of trauma, surgical intake antibiotics and or steroids was secured. Information abou t of extent and infection, site, the type management, if any were also included. Duplicate swabs from chronic discharging sinuses & gaping post-surgical or wounds or post-traumatic opera ti ve from cases of and specimen AHO septic arthri tis were taken. One of was the. dipped portion specimen into Stuart’s transport medium, inoculated onto plates of blood and MacConkey’s and incubated agar agar aerobically overnight at 37°C. The other portion was dipped into brain heart infusion broth, inoculated onto plates of SDA and incubated aerobically at 28°C for 48 hours. Isolates were fully identified by using Gram stained films & biochemical tests. The results showed that: - Males were more commonly affected than females. (69.8 & 30.2 respectively). - Bone infection was localized mainly in lower limbs and femur was the most commonly affected, while knee was the commonest involved joint in septic arthri ti s . . - Bone infection constituted 89.6 of the studied cases while joint infections constituted 10.4.. _The inoculation route was the commonest route in bone infection represented 64.2 followed by the haematogenous route. (30.5) and extension route (5.3) while in septic arthritis, the commonest route of infection was the haematogenous constituted 72.7 of cases followed by the inoculation route (27.3) while no cases through the extension route. --The majority of cases of acute haematogenous osteomyelitis (90.9) occrured below 20 years of age. - Q.aureus was the most frequently isolated organism in both bone and joint infections.