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Abstract Juvenile polyps are hamartomatous lesions that present in both children and adults and are more frequently found in colon but also may occur in stomach, duodenum and small intestine (Ladd and Grosfeld, 2006). Juvenile polyps can occur in a sporadic form or can be a part of juvenile polyposis syndrome. Isolated Juvenile polyp is the most common childhood bowel tumor accounting for 75-95% of childhood polyps, occurring in perhaps as many as 5% of all children (Merge and Howe, 2004). Juvenile polyps may present at any time, from the neonatal period into adulthood, with the peak incidence occurs between 2 and 5 years up to 10 years of age, being less common beyond 15 years of age and exceedingly unusual in infants less than 12 months of age (Waitayakul et al., 2004). The colonic mucosa adjacent to a juvenile polyp was found to show special macroscopic features of chicken skin appearance. Hence the aim of this work was to study the histological features of JPs and compare this with histological features of distant colonic mucosal biopsy that are presumably normal |