الفهرس | Only 14 pages are availabe for public view |
Abstract The brain is a very complex organ, which interacts with numerous physiological functions of the body. The anesthesiologist can alter the cerebral physiology and improve the physiological reserve of the brain with the purpose of providing cerebral protection. However, a lack of understanding of its physiology may also be contributed to the development of secondary brain injuries. The brain requires large amounts of energy to maintain cellular integrity and support neurotransmission. Despite these large requirements, the brain has virtually no glucose reserve. It is the organ with the highest rate of oxygen consumption. Most of the oxygen consumption in the brain is used to maintain cellular integrity, electrogenesis and sustain cellular transport mechanism such as reuptake of neurotransmitters When the supply of oxygen decreases, electrogenesis is impaired and quickly ceases. Cerebral auto regulation and cerebrovascular reactivity are impaired and the neuronal integrity Jeopardized. |