الفهرس 
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Abstract
Antibiotics are widely used in poultry farms not only for treatment and control of infectious diseases but also as feed additives for growth promotion. The extensive use of these drugs in laying hens leads to appearance of the problem of drug residues as a result of excretion of such drugs in the eggs during and after treatment which have harmful effect on the consumers.
So the aim of this work was the detection of minimal inhibitory concentration of enrofloxacin and flumequine giving inhibition zo,ne by using Microbiological assay technique and determination of the withdrawal time of enrofloxacin and flurnequine after oral application as well as the incidence of thhibitory substance in table eggs marketed in Alexandria, Behera and Kafr E1-Sheikh governorates.
1. Detection of minimal inhibitory concentration:
In vitro:
Agar diffusion test, E. coil strain and standard agar II were used. The detection limits of the reference substances solutions were 0.022 and 0.04 g!ml for enrofloxacin and flumequine, respectively.
E. coil as a test organism is more sensitive for determination of enrofloxacin and flumequine residues in egg contents than Pseudomonas fluorescens, Klebsiella pneumoniae and Bacillus subtilis.