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Abstract
Hepatocellular carcinoma (HCC) is one of the most commonly occurring solid tumors worldwide. Percutaneous acetic acid injection (PAI) and radiofrequency ablationare options for treatment.
Aim of the work: The aim is to compare the efficacy and safety of combined radiofrequency and acetic acid injection versus radiofrequency alone for ablation of HCC.
Patients and methods: This study was conducted on 40 patients having HCC. Group 1 (20 patients) was subjected to radiofrequency ablation preceeded by intra-tumoral acetic acid injection (RFA + AA). Group 2 (20 patients) was subjected to RFA alone.
Results: The procedure was successful in 18 (90%) patients of group 1 and in 15 (75%) of group 2.
Conclusion: RFA+AA is more effective than RFA alone as acetic acid injection may enhance the ablation induced by RFA.