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العنوان
Red cell phenotyping among multitransfused thalassemic patients /
المؤلف
EL-Emery, Asmaa Ahmed Ahmed.
هيئة الاعداد
باحث / أسماء أحمد أحمد العميرى
مشرف / منال أبراهيم فوده
مشرف / دعاء محمود الغنام
مشرف / شيرين محمد عبدالعزيز
الموضوع
Bone Marrow Diseases. Anemia.
تاريخ النشر
2015.
عدد الصفحات
118 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض الدم
تاريخ الإجازة
01/01/2015
مكان الإجازة
جامعة المنصورة - كلية الطب - clinical pathology
الفهرس
Only 14 pages are availabe for public view

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from 131

Abstract

This study aimed to : Thalassemia is an inherited hemolytic disorder caused by partial or complete deficiency ofα or β globin chain synthesis. Regular transfusions are essential for patients with thalassemia to maintain growth and development during childhood and to sustain good quality of life during adulthood. Transfusion therapy with packed red blood cells (PRBCs) is a common practice in the treatment and prevention of many diseases like sickle cell anemia, thalasemia and aplastic anemia.The majority of these patients receive transfusions of PRBCs at some stage of life and some of them become chronic receivers of blood transfusion The study of erythrocyte phenotypes of blood groups in patients and blood donors provides a comparison of the frequency of the most immunogenic genes in each system, being important to decrease the risk of alloimmunization, in addition to estimating the availability of compatible blood, especially in cases of previous delayed hemolytic transfusion reaction DHTR).