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العنوان
Evaluation of electroencephalographic Patterns in children with attention-deficit/hyperactivity disorder /
المؤلف
Mahmoud, Mahmoud Radwan.
هيئة الاعداد
باحث / محمود رضوان محمود
مشرف / مصطفى محمود العيوطي
مشرف / ميادة صبري الحسيني
الموضوع
Hyperactivity Disorder. Electroencephalographic - Childern.
تاريخ النشر
2018.
عدد الصفحات
92 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
01/12/2018
مكان الإجازة
جامعة المنصورة - كلية الطب - Department of Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 105

from 105

Abstract

Introduction: ADHD is one of the most common neurodevelopmental disorders and it occurs up to 8-10% of school age children. The three subtypes of ADHD including inattentive, hyperactivity, and combined. Until now, the exact pathological cause of ADHD is not known. It is thought to be the result of complex interactions between genetic, environmental, and neurobiological factors.
The aim of work: To explore the relationship between EEG profile of attention deficit hyperactive disorders (ADHDs) children and their clinical presentation and to find out if starting antiepileptic drugs for ADHD patients with abnormal EEG pattern will improve their outcome.
Research Plan: 60 children were enrolled in the study. First EEG was done to all children, then those with abnormal EEG study were randomly assigned to two groups, one received antiepileptic drugs and the other recieved the traditional ADHD therapy
Results: Our study demonstrated that abnormal EEG pattern was documented in 40 % of children at time of diagnosis. The combined subtype was the predominant clinical presentation in 79.2 % of patients with abnormal EEG. Also, 41.7% of them were rated as very severe according to CPRS.The main outcome of the study was to evaluate the improvement in ADHD-rating scale in patients with abnormal EEG who received AEDs.The number of children showed improvement in severity scale was statistically significantly higher in patients received AEDs compared to those not received AEDs.AEDs were tolerated in most of children as no complications were reported apart from gastric upset in 2 cases and sedation in 1 case (from total 12 cases). Thus, the use of antiepileptic drugs did not increase the incidence of side effects in study group
Conclusion:
• Abnormal EEG pattern was documented in 40% of our study subjects.
• Presence of abnormal changes in EEG might explain the clinical improvement of these children to antiepileptic drugs.
• The most common clinical presentation of ADHD was the combined subtype, it was not related to a certain EEG pattern.
• Anti-epileptic drugs can be a well-tolerated and effective treatment in some cases of ADHD associated with abnormal EEG findings