الفهرس 
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Abstract
Hepatitis C is a disease of significant global impact. chronic HCV infection is a serious, progressive, and potentially life-threatening disease. Aim: The aim of this study was to evaluate the effect of implementing infection control guideline on health care workers’ knowledge and practice. Design: Quasi-experimental research design was used in this study. Setting: The study was conducted at the Egyptian Liver Institute in Sherbein Dakahlia. Sample: A convenience sample of 61 health care workers constituted the study sample. Tools of the study: Two tools were used to collect the necessary data for this study: Tool I: Health care workers knowledge questionnaire: divided into 3 parts: Part 1: Socio-demographic data, Part 2: Hepatitis C knowledge assessment questionnaire, Part3: Infection control precautions knowledge assessment questionnaire. Tool II: Health care workers practice checklist. Result: The results of this study revealed that there was no statistically significant correlation between overall knowledge and overall practice pre, immediately post and after 3 months. Conclusion: There was improvement in health care workers’ knowledge in immediate and after 3 months of implementation of infection control guideline. Recommendation: The study recommended periodic refreshing training courses should be provided at regular intervals in order to keep the health care workers and newly joined health care workers of updating knowledge and practices.