الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 113 |  |  |
| | | from | 113 | | |
Abstract
Objectives: The purpose of this clinical investigation was to assess the regenerative potential of local application of metformin gel in enhancement of bone healing after surgical removal of intra-bony jaw lesions. Patients and methods: Fourteen patients received surgical removal of intrabony jaw lesions ,they were randomly and equally categorized in two groups. In the control group,the jaw cavity was kept empty, while in the Study group , metformin gel was applied to fill the jaw cavity after lesion removal . Clinical scales were assessed immediately and seven days later ,but radiographic scales were assessed immediately and at 12 months. Results: there were insignificant difference among two groups as regard bone density of newelyformed bone and bone defect volume. Conclusions:from a clinical point of view, Metformin is considered a safe and well tolerable material when applied locally. Although there is doubt of its osteo-inductive property which hinder its use for enhancing bone healing.