الفهرس 
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Abstract
Introduction:. :Defecation - related functional gastrointestinal disorders are common problems in childhood. Children with neurodevelopmental disorder, including ASD, are regularly affected by gastrointestinal problems and dysbiosis of gut microbiota. The aim of work The present study aimed to assess the prevalence of ASD symptoms in patients with FDD and to discover, its demographic and clinical predictors in those patients. Research Plan:.The study included 60 children with FDD diagnosed according to Rome IV criteria. In the present study, the included patients had an age of 7.5 ± 2.9 years and most of them were males 43 (71.7%). Results:Conclusion:. In the present study, the reported functional defecation disorders included functional constipation (FC) in 46 patients (76.7 %) and functional non-retentive fecal incontinence (FNRFI) in 14 patients (23.3 %). In children with FC, the reported age of onset was 4.4 ± 1.1 years and duration of symptoms was 3.3 ± 2.3 years. Bleeding per rectum was reported in 15.2 % of patients and 8.7 % of patients had affected siblings. Regarding the prevalence of ASD in the studied FC patients, the current study could identify ASD in 16 patients (34.8 %). In the current study, comparison between FC patients with ASD and patients without regarding the reported Rome IV criteria showed that patients with ASD had significantly higher frequency of few defecations and fecal incontinence. In addition, it was found that patients with ASD had significantly higher total criteria count when compared with patients without ASD. Moreover, the present study found that patients with ASD had significantly younger age of onset and longer symptom duration. In patients with FNRFI, 3 patients (21.4 %) were diagnosed with ASD. Moreover, it was found that ASD patients had significantly younger age of onset and longer duration of symptoms. CONCLUSIONS •The current study could identify ASD in 16 patients (34.8 %) with FC. •Patients with ASD had significantly higher frequency of few defecations and fecal incontinence and higher total criteria count when compared with patients without ASD. •Patients with ASD had significantly younger age of onset and longer symptom duration. •In patients with FNRFI, 3 patients (21.4 %) were diagnosed with ASD. Moreover, it was found that ASD patients had significantly younger age of onset and longer duration of symptoms.