الفهرس 
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Abstract
ABSTRACT : Chapter (1): Synthesis of novel meso-substituted porphyrins 4a-g from the condensation of their corresponding aldehyde derivatives 3a-g with pyrrole in existence of p-toluenesulfonic acid as shown in (Scheme 2) and the synthesis of metalloporphyrins 5-11 by the one-pot reaction which increased the yield (82–87 %) compared to the two-steps method in which the free porphyrin has to be prepared before the following step in which the metal ion is added (Scheme 4). Chapter (2): Synthesis of some novel phthalocyanines containing peripherally functionalized fused compounds from the reaction of the newly different dicarbonitrile derivatives with DDQ by heating at a boiling temperature under N2 gas (Schemes 5-11). Chapter (3): Pharmacology of porphyrins and some of their metalloporphyrins as antiviral and antitumor agents, the results showed that compounds 4g, 6 and 10 have the highest cytotoxic activities. Also Pharmacology of phthalocyanine derivatives as antioxidant and antitumor agents, the results showed that compounds 28 and 29 have the highest cytotoxic activities. Chapter (4): Industrial application as fluorescence solid study for some novel porphyrins and some of their metallo-porphyrins, the results showed that the order of the fluorescence intensity of the porphyrins and metallo-porphyrins was 10 > 11 > 4e > 4b > 4d > 6 > 7. Chapter (5): Solvent effects on the UV-visible absorption spectra of some new thiophene dyes 37a-d which were successfully prepared and their absorption spectra were studied in MeOH, CHCl3, and DMF The substituent at the second position of the thiophene ring clearly affecting the absorption maxima to follow this order in DMF: COPh (37b: λmax = 654) > COMe (37a: λmax = 646) > COOEt (37c: λmax = 642) > CN (37d: λmax = 626).