الفهرس 
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Abstract
Title : ”Evaluation of NAFLD Associated Liver Fibrosis by Hepatic Artery Resistive Index and its Correlation with Clinical, Biochemical and Radiological Parameters” Introduction : Previous studies have demonstrated that hepatic artery resistive index (HARI) is significantly altered in patients with NAFLD, with significant reduction of this parameter with increasing of severity of diffuse fatty liver disease. Conversely, HARI in cirrhotic patients tends to increase, but there is no evidence so far of a putative correlation between HARI and severity of fibrosis in NAFLD patients. Aim of work : The aim of this study was to investigate a possible correlation between hepatic artery resistive index and stage of liver fibrosis associated with NAFLD. Patients and methods : This study was carried out on 100 patients (28 males and 72 females) with NAFLD aged between (30-66) years old recruited from out and inpatient clinic of Tropical medicine department, Mansoura University, Dakahlya, Egypt between June 2018 and May 2021. All patients aged 18 years old and above with body mass index (BMI (more than 25 and evidence of any grade of fatty liver on ultrasonography (USG) was included in this study. All subjects had undergone the following: detailed history taking and clinical assessment: measurement of weight, height, waist circumference and BMI calculation., pelvi–abdominal US as a screening tool , Doppler on hepatic artery to measure hepatic artery resistive index, transient elastography to determine degree of steatosis & fibrosis. Lab work up, non-invasive scores for the assessment of liver fibrosis (APRI, FIB-4, NAFLD fibrosis score) were calculated using standard formulas. Results and discussion : Our results showed that there was statistically significant positive correlation of HARI with Age, Hba1c, LDL, FIB4, NFS and LSM, While a statistically significant negative correlation of HARI with CAP was detected. We detect some predictors of fibrosis: Age, Hba1c, thrombocytopenia, DM, Family History of metabolic disease, splenomegaly, decreased CAP, APRI, NFS and HARI. Summary & conclusions : HARI is a doppler parameter that correlates with other non-invasive methods of assessment of fibrosis e.g, FIB4, NFS and LSM and may provide an easy, applicable, available tool for monitoring of patients with NAFLD