الفهرس 
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Abstract
Due to its environmentally friendly, non-toxic, and economically advantageous properties, the production of zinc oxide nanoparticles (ZnO NPs) by fungi is becoming a crucial nanotechnology subject. Fusarium oxysporum has been used as a stabilizing and reducing agent in the mycosynthesis of ZnO NPs. Various characterization approaches, including UV-Vis spectroscopy and X-ray diffraction (XRD), confirmed the synthesized nanoparticles’ average size (26.3 nm). In addition, Fourier transform infrared (FTIR) spectroscopy was employed. Since, FTIR pattern results revealed the presence of reducing and stabilizing agents (e.g. carboxylic acid, and amines). Furthermore, transmission electron microscopy (TEM) was used to describe the size and shape of nanoparticles. Since, TEM images revealed that ZnO NPs had a crystalline structure with hexagonal wurtzite form (5–47 nm size). The antibacterial activity of ZnO NPs against Gram-positive and Gram-negative clinical bacterial isolates was remarkable. Since, ZnO NPs have showed good antibacterial effect against Gram-negative bacteria MRSA rather than Escherichia coli. However, at a dosage of 50, 100 and 150 mg/ml, ZnO NPs had slightly stronger antibacterial capabilities of Bacillus subtilis than Staphylococcus aureus of Gram-positive bacteria. The ZnO NPs demonstrated a good either scavenging activities of 26.69 mg/mL at IC50 and of a cytotoxic activity IC50 of 197±0.8956 μg/mL. According to the catalytic activity results, the biosynthesized ZnO NPs had an excellent catalytic removal activity against Methyl Blue within 180 min. Therefore, the eco-friendly biosynthesized ZnO NPs using F. oxysporum shows optimistic properties for further applications in medical, pharmaceutical, biological, and industrial fields.