الفهرس | Only 14 pages are availabe for public view |
Abstract Tuberculosis is a chronic granulomatous infection in which the T-cell mediated immune response plays an important role in the pathogenesis of the disease and also in the protective immunity against the tubercle bacillus (Shiratuschi and Tsuyuguchi, 1984). The NK cells also may have a possible role in the cell mediated immunity in tuberculosis (Yonedia, et al., 1983). This work was intended to through a high light on the T-cell, T-subsets and Nk cell changes in tuberculo¬sis, which may give a clue for diagnosis, severity and prognosis of the disease. The study included forty two tuberculous children selected from patients admitted in Pediatric Department, Mansoura University Hospital and Mansoura Chest Hospital in the period between September 1987 and April 1990. The control group comprised fifteen healthy children with matched age and sex. All patients were subjected to full history tak¬ing, through clinical examination, tuberculin skin testing, Zeihl Neelson Staining of the availbe sputum, aspirate or tissue, ESR, full blood picture, X-ray chest and the special investigations that deffered according |